Type 1 diabetes, strict definition, subgroup 2

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

FinnGen phenotype data

Filter registries None

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Check pre-conditions

Pre-conditions EVENT_AGE<40
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Include endpoints

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Check conditions

not E4_DM2
and not PANCREATITIS
and not INSULIN_INTER_AND_LONG
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST

Apply sex-specific rule None

diagram downward connector T1D_STRICT2

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 69 32 37
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 18.42 20.78 16.37

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: T1D_STRICT2 – Type 1 diabetes, strict definition, subgroup 2
GWS hits:

Survival analyses between endpoints

Plot

before Type 1 diabetes, strict definition, subgroup 2
after Type 1 diabetes, strict definition, subgroup 2

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Drugs most likely to be purchased after Type 1 diabetes, strict definition, subgroup 2