Diabetic polyneuropathy

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G63.2*E10.4, G63.2*E11.4
Cause of death: ICD-10 G63.2*E10.4, G63.2*E11.4

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector DM_POLYNEURO

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 453 144 309
Unadjusted prevalence (%) 0.17 0.10 0.27
Mean age at first event (years) 63.39 63.22 63.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 7.07 [3.97, 12.60] 3.3e-11 99
15 years 0.05 7.77 [4.67, 12.92] 2.7e-15 92
5 years - - - -
1 year - - - -

Correlations

Index endpoint: DM_POLYNEURO – Diabetic polyneuropathy
GWS hits: 0

Survival analyses between endpoints

Plot

before Diabetic polyneuropathy
after Diabetic polyneuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic polyneuropathy