Other and unspecified polyneuropathies, also in other diseases

DOID EFO MESH SNOMED PheWeb

chronic inflammatory demyelinating polyradiculoneuropathy: A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G61.1#, G61.8, G61.9, G62.8, G62.9, G63*, G63.0*B02.29

Hospital discharge: ICD-9 357[8-9]

Hospital discharge: ICD-8 3540[8-9]

Cause of death: ICD-10 G61.1#, G61.8, G61.9, G62.8, G62.9, G63*, G63.0*B02.29

Cause of death: ICD-9 357[8-9]

Cause of death: ICD-8 3540[8-9]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

G6_POLYOTHUNS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified polyneuropathies, also in other diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Diabetic polyneuropathy

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3260	1305	1955
Unadjusted prevalence (%)	1.25	0.89	1.73
Mean age at first event (years)	60.59	58.63	61.89

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.73 [2.52, 5.51]	4.6e-11	538
15 years	0.03	3.84 [2.64, 5.60]	2.2e-12	495
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: G6_POLYOTHUNS – Other and unspecified polyneuropathies, also in other diseases
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other and unspecified polyneuropathies, also in other diseases
after Other and unspecified polyneuropathies, also in other diseases

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Table

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Drugs most likely to be purchased after Other and unspecified polyneuropathies, also in other diseases

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