Diabetic nephropathy

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 N08.3*
Cause of death: ICD-10 N08.3*

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector DM_NEPHROPATHY

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3957 1473 2484
Unadjusted prevalence (%) 1.52 1.00 2.20
Mean age at first event (years) 52.48 48.42 54.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 12.34 [9.34, 16.31] 7.1e-70 979
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: DM_NEPHROPATHY – Diabetic nephropathy
GWS hits: 7

Survival analyses between endpoints

Plot

before Diabetic nephropathy
after Diabetic nephropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic nephropathy