Secondary systemic amyloidosis

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E85.3
Cause of death: ICD-10 E85.3

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_AMYL_SCNDSYST

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E85
Name in latin Amyloidosis systemica secundaria

Summary Statistics

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Key figures

All Female Male
Number of individuals 55 34 21
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 59.71 59.47 60.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: E4_AMYL_SCNDSYST – Secondary systemic amyloidosis
GWS hits:

Survival analyses between endpoints

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Plot

before Secondary systemic amyloidosis
after Secondary systemic amyloidosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Secondary systemic amyloidosis

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