Nontoxic multinodular goitre

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E04.2
Hospital discharge: ICD-9 2411
Hospital discharge: ICD-8 241
Cause of death: ICD-10 E04.2
Cause of death: ICD-9 2411
Cause of death: ICD-8 241

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_GOITREMULTINOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica multinodularis

Summary Statistics

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Key figures

All Female Male
Number of individuals 4095 3512 583
Unadjusted prevalence (%) 1.57 2.39 0.52
Mean age at first event (years) 51.85 50.92 57.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.11 [0.82, 1.49] 5.1e-1 310
15 years 0.01 1.33 [1.02, 1.74] 3.5e-2 219
5 years 0.00 1.78 [1.31, 2.41] 2.1e-4 66
1 year 0.00 2.23 [1.29, 3.84] 4.0e-3 15

Correlations

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Index endpoint: E4_GOITREMULTINOD – Nontoxic multinodular goitre
GWS hits: 29

Survival analyses between endpoints

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Plot

before Nontoxic multinodular goitre
after Nontoxic multinodular goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic multinodular goitre

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