Nontoxic multinodular goitre

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E04.2
Hospital discharge: ICD-9 2411
Hospital discharge: ICD-8 241
Cause of death: ICD-10 E04.2
Cause of death: ICD-9 2411
Cause of death: ICD-8 241

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_GOITREMULTINOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica multinodularis

Summary Statistics

Key figures

All Female Male
Number of individuals 4095 3512 583
Unadjusted prevalence (%) 1.57 2.39 0.52
Mean age at first event (years) 51.85 50.92 57.50


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.11 [0.82, 1.49] 5.1e-1 310
15 years 0.01 1.33 [1.02, 1.74] 3.5e-2 219
5 years 0.00 1.78 [1.31, 2.41] 2.1e-4 66
1 year 0.00 2.23 [1.29, 3.84] 4.0e-3 15


Index endpoint: E4_GOITREMULTINOD – Nontoxic multinodular goitre
GWS hits: 29

Survival analyses between endpoints


before Nontoxic multinodular goitre
after Nontoxic multinodular goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic multinodular goitre