Other and/or unspecified nontoxic goitre

goiter: Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E04.8, E04.9
Hospital discharge: ICD-9 2419
Cause of death: ICD-10 E04.8, E04.9
Cause of death: ICD-9 2419

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_GOITRENAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1519 1286 233
Unadjusted prevalence (%) 0.58 0.88 0.21
Mean age at first event (years) 54.25 53.40 58.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.17 [0.79, 1.74] 4.3e-1 101
15 years 0.01 1.53 [1.05, 2.22] 2.6e-2 77
5 years 0.00 2.82 [1.88, 4.24] 6.1e-7 36
1 year 0.00 5.16 [2.78, 9.58] 2.0e-7 12

Correlations

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Index endpoint: E4_GOITRENAS – Other and/or unspecified nontoxic goitre
GWS hits: 5

Survival analyses between endpoints

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Plot

before Other and/or unspecified nontoxic goitre
after Other and/or unspecified nontoxic goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and/or unspecified nontoxic goitre

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