Nontoxic single thyroid nodule

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E04.1
Hospital discharge: ICD-9 2410|2462
Cause of death: ICD-10 E04.1
Cause of death: ICD-9 2410|2462

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_GOITRENOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica uninodularis

Summary Statistics

Key figures

All Female Male
Number of individuals 1349 1098 251
Unadjusted prevalence (%) 0.52 0.75 0.22
Mean age at first event (years) 50.52 48.99 57.21


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.02 [0.58, 1.81] 9.4e-1 58
15 years 0.01 1.18 [0.72, 1.94] 5.2e-1 41
5 years 0.00 1.60 [0.82, 3.11] 1.7e-1 12
1 year - - - -


Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 1

Survival analyses between endpoints


before Nontoxic single thyroid nodule
after Nontoxic single thyroid nodule

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic single thyroid nodule