Nontoxic single thyroid nodule

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E04.1
Hospital discharge: ICD-9 2410|2462
Cause of death: ICD-10 E04.1
Cause of death: ICD-9 2410|2462

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_GOITRENOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica uninodularis

Summary Statistics

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Key figures

All Female Male
Number of individuals 1349 1098 251
Unadjusted prevalence (%) 0.52 0.75 0.22
Mean age at first event (years) 50.52 48.99 57.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.02 [0.58, 1.81] 9.4e-1 58
15 years 0.01 1.18 [0.72, 1.94] 5.2e-1 41
5 years 0.00 1.60 [0.82, 3.11] 1.7e-1 12
1 year - - - -

Correlations

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Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 1

Survival analyses between endpoints

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Plot

before Nontoxic single thyroid nodule
after Nontoxic single thyroid nodule

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic single thyroid nodule

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