Mixed hyperlipidaemia

obsolete_familial combined hyperlipidemia: ['A type of familial lipid metabolism disorder characterized by a variable pattern of elevated plasma CHOLESTEROL and/or TRIGLYCERIDES. Multiple genes on different chromosomes may be involved, such as the major late transcription factor (UPSTREAM STIMULATORY FACTORS) on CHROMOSOME 1.']

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E78.2
Hospital discharge: ICD-9 2722
Cause of death: ICD-10 E78.2
Cause of death: ICD-9 2722

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_HYPERLIPMIX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E78

Summary Statistics

Key figures

All Female Male
Number of individuals 664 231 433
Unadjusted prevalence (%) 0.26 0.16 0.38
Mean age at first event (years) 55.12 56.44 54.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.86 [1.68, 4.87] 1.1e-4 114
15 years 0.02 3.38 [2.10, 5.43] 5.0e-7 96
5 years 0.01 4.73 [2.98, 7.53] 5.4e-11 34
1 year - - - -

Correlations

Index endpoint: E4_HYPERLIPMIX – Mixed hyperlipidaemia
GWS hits: 3

Survival analyses between endpoints

Plot

before Mixed hyperlipidaemia
after Mixed hyperlipidaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Mixed hyperlipidaemia