Hyperfunction of pituitary gland, other and/or unspecified

hyperpituitarism: Disease of the glandular, anterior portion of the pituitary (pituitary gland, anterior) resulting in hypersecretion of adenohypophyseal hormones such as growth hormone; prolactin; thyrotropin; luteinizing hormone; follicle stimulating hormone ; and adrenocorticotropic hormone. Hyperpituitarism usually is caused by a functional adenoma.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E22.9
Hospital discharge: ICD-9 2531X
Hospital discharge: ICD-8 25301
Cause of death: ICD-10 E22.9
Cause of death: ICD-9 2531X
Cause of death: ICD-8 25301

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_HYPERPITNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 E22
Name in latin Hyperfunctio hypophysis non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 38 22 16
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 51.75 47.70 57.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: E4_HYPERPITNAS – Hyperfunction of pituitary gland, other and/or unspecified
GWS hits:

Survival analyses between endpoints

Plot

before Hyperfunction of pituitary gland, other and/or unspecified
after Hyperfunction of pituitary gland, other and/or unspecified

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Drugs most likely to be purchased after Hyperfunction of pituitary gland, other and/or unspecified