Autoimmune thyroiditis

autoimmune thyroid disease: Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E06.3
Hospital discharge: ICD-9 2452
Cause of death: ICD-10 E06.3
Cause of death: ICD-9 2452

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_THYROIDITAUTOIM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E06
Name in latin Thyreoiditis autoimmunis

Summary Statistics

Key figures

All Female Male
Number of individuals 301 256 45
Unadjusted prevalence (%) 0.12 0.17 0.04
Mean age at first event (years) 41.81 40.96 46.60


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.19 [0.40, 3.53] 7.6e-1 12
15 years - - - -
5 years - - - -
1 year - - - -


Index endpoint: E4_THYROIDITAUTOIM – Autoimmune thyroiditis
GWS hits: 2

Survival analyses between endpoints


before Autoimmune thyroiditis
after Autoimmune thyroiditis

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Drugs most likely to be purchased after Autoimmune thyroiditis