Autoimmune thyroiditis

autoimmune thyroid disease: Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E06.3
Hospital discharge: ICD-9 2452
Cause of death: ICD-10 E06.3
Cause of death: ICD-9 2452

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_THYROIDITAUTOIM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E06
Name in latin Thyreoiditis autoimmunis

Summary Statistics

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Key figures

All Female Male
Number of individuals 301 256 45
Unadjusted prevalence (%) 0.12 0.17 0.04
Mean age at first event (years) 41.81 40.96 46.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.19 [0.40, 3.53] 7.6e-1 12
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: E4_THYROIDITAUTOIM – Autoimmune thyroiditis
GWS hits: 2

Survival analyses between endpoints

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Plot

before Autoimmune thyroiditis
after Autoimmune thyroiditis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Autoimmune thyroiditis

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