Graves disease: Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland ( hyperthyroidism ).It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism andoccurs mostoften in women over age 20. However, the disorder may occur at any age and may affect males as well.Treatmentmayinclude radioiodine therapy , antithyroid drugs, and/or thyroid surgery.
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E4_THYTOXGOITDIF
Extra metadata
List of similar endpoints to
Thyrotoxicosis with diffuse goitre
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2777 | 2305 | 472 |
| Unadjusted prevalence (%) | 1.07 | 1.57 | 0.42 |
| Mean age at first event (years) | 48.50 | 47.83 | 51.74 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.03 | 1.84 [1.26, 2.67] | 1.4e-3 | 116 |
| 15 years | 0.01 | 1.95 [1.31, 2.91] | 1.1e-3 | 94 |
| 5 years | 0.00 | 2.68 [1.69, 4.24] | 2.7e-5 | 36 |
| 1 year | 0.00 | 5.32 [2.84, 9.96] | 1.8e-7 | 13 |
Index endpoint: E4_THYTOXGOITDIF – Thyrotoxicosis with diffuse goitre
GWS hits: 10
before Thyrotoxicosis with diffuse goitre
after Thyrotoxicosis with diffuse goitre
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