Alcohol dependence

alcohol dependence: Physical and psychological dependence on alcohol.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F10.2
Hospital discharge: ICD-9 303
Hospital discharge: ICD-8 303
Cause of death: ICD-10 F10.2
Cause of death: ICD-9 303
Cause of death: ICD-8 303

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_ALCOHOL_DEPENDENCE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 F10

Summary Statistics

Key figures

All Female Male
Number of individuals 7028 1995 5033
Unadjusted prevalence (%) 2.70 1.36 4.45
Mean age at first event (years) 42.21 40.82 42.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.28 [3.28, 5.60] 1.3e-26 1385
15 years 0.03 5.25 [4.22, 6.52] 1.1e-50 1083
5 years - - - -
1 year - - - -

Correlations

Index endpoint: F5_ALCOHOL_DEPENDENCE – Alcohol dependence
GWS hits: 3

Survival analyses between endpoints

Plot

before Alcohol dependence
after Alcohol dependence

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alcohol dependence