Alcohol use disorder, ICD-based

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F10.1, F10.2
Hospital discharge: ICD-9 303
Hospital discharge: ICD-8 303
Cause of death: ICD-10 F10.1, F10.2
Cause of death: ICD-9 303
Cause of death: ICD-8 303

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector AUD

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 10685 3391 7294
Unadjusted prevalence (%) 4.11 2.31 6.45
Mean age at first event (years) 43.37 40.47 44.72

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.47 [4.48, 6.67] 1.4e-62 1837
15 years 0.04 6.70 [5.70, 7.87] <1e-100 1492
5 years 0.01 11.46 [10.00, 13.13] <1e-100 691
1 year 0.00 23.48 [19.48, 28.31] <1e-100 273

Correlations

Index endpoint: AUD – Alcohol use disorder, ICD-based
GWS hits: 6

Survival analyses between endpoints

Plot

before Alcohol use disorder, ICD-based
after Alcohol use disorder, ICD-based

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alcohol use disorder, ICD-based