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Bipolar affective disorders

DOIDEFOMESHSNOMED PheWeb

bipolar disorder: A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F31
Hospital discharge: ICD-9 296[2-7]
Hospital discharge: ICD-8 296
Hospital discharge: excluded ICD-8 2960|29699
Cause of death: ICD-10 F31
Cause of death: ICD-9 296[2-7]
Cause of death: ICD-8 296
Cause of death: excluded ICD-8 2960|29699

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_BIPO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F30-F39
Name in latin Perturbatio affectiva bipolaris

Summary Statistics

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Key figures

All Female Male
Number of individuals 5091 3184 1907
Unadjusted prevalence (%) 1.96 2.17 1.69
Mean age at first event (years) 39.23 38.05 41.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.00 [2.08, 4.33] 3.6e-9 224
15 years 0.02 3.62 [2.64, 4.96] 1.4e-15 175
5 years 0.00 4.50 [3.06, 6.62] 2.3e-14 57
1 year 0.00 6.81 [3.80, 12.21] 1.1e-10 15

Correlations

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Index endpoint: F5_BIPO – Bipolar affective disorders
GWS hits: 0

Survival analyses between endpoints

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Plot

before Bipolar affective disorders
after Bipolar affective disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Bipolar affective disorders

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