Manic episode

bipolar disorder: A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F30
Cause of death: ICD-10 F30

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_MANIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F30-F39
Name in latin Mania

Summary Statistics

Key figures

All Female Male
Number of individuals 710 390 320
Unadjusted prevalence (%) 0.27 0.27 0.28
Mean age at first event (years) 43.19 42.73 43.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.17 [1.63, 6.20] 7.2e-4 42
15 years 0.02 3.38 [1.85, 6.16] 7.2e-5 34
5 years 0.01 4.94 [2.54, 9.60] 2.5e-6 15
1 year - - - -

Correlations

Index endpoint: F5_MANIA – Manic episode
GWS hits: 1

Survival analyses between endpoints

Plot

before Manic episode
after Manic episode

loading spinner Loading survival analyses plot