Manic episode

bipolar disorder: A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F30
Cause of death: ICD-10 F30

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_MANIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F30-F39
Name in latin Mania

Summary Statistics

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Key figures

All Female Male
Number of individuals 710 390 320
Unadjusted prevalence (%) 0.27 0.27 0.28
Mean age at first event (years) 43.19 42.73 43.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.17 [1.63, 6.20] 7.2e-4 42
15 years 0.02 3.38 [1.85, 6.16] 7.2e-5 34
5 years 0.01 4.94 [2.54, 9.60] 2.5e-6 15
1 year - - - -

Correlations

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Index endpoint: F5_MANIA – Manic episode
GWS hits: 1

Survival analyses between endpoints

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Plot

before Manic episode
after Manic episode

loading spinner Loading survival analyses plot