Profound mental retardation

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F73
Hospital discharge: ICD-9 3182
Hospital discharge: ICD-8 314
Cause of death: ICD-10 F73
Cause of death: ICD-9 3182
Cause of death: ICD-8 314

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_PRORET

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F70-F79
Name in latin Retardatio mentalis profunda

Summary Statistics

Key figures

All Female Male
Number of individuals 18 12 6
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 31.63 34.60 25.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: F5_PRORET – Profound mental retardation
GWS hits:

Survival analyses between endpoints

Plot

before Profound mental retardation
after Profound mental retardation

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Drugs most likely to be purchased after Profound mental retardation