Post-traumatic stress disorder

post-traumatic stress disorder: An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F43.1
Hospital discharge: ICD-9 3098X
Cause of death: ICD-10 F43.1
Cause of death: ICD-9 3098X

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_PTSD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F43
Name in latin Perturbatio stressualis posttraumatica

Summary Statistics

Key figures

All Female Male
Number of individuals 1312 1043 269
Unadjusted prevalence (%) 0.50 0.71 0.24
Mean age at first event (years) 35.55 34.59 39.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.56 [1.34, 4.90] 4.4e-3 29
15 years 0.02 2.56 [1.35, 4.88] 4.2e-3 24
5 years - - - -
1 year - - - -

Correlations

Index endpoint: F5_PTSD – Post-traumatic stress disorder
GWS hits: 0

Survival analyses between endpoints

Plot

before Post-traumatic stress disorder
after Post-traumatic stress disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Post-traumatic stress disorder