Fibrosis of liver

cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K74.0
Cause of death: ICD-10 K74.0

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector FIBROLIV

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Fibrosis hepatis

Summary Statistics

Key figures

All Female Male
Number of individuals 84 46 38
Unadjusted prevalence (%) 0.03 0.03 0.03
Mean age at first event (years) 52.31 50.67 54.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: FIBROLIV – Fibrosis of liver
GWS hits: 0

Survival analyses between endpoints

Plot

before Fibrosis of liver
after Fibrosis of liver

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Fibrosis of liver