Gout, strict definition

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

FinnGen phenotype data
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Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC M04AA01|M04AA03|M04AB01|M04AB03
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

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Check conditions

GOUT_IDIOP_NOS

Apply sex-specific rule None

diagram downward connector GOUT_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 2379 453 1926
Unadjusted prevalence (%) 0.91 0.31 1.70
Mean age at first event (years) 61.71 65.85 60.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.32 [1.72, 3.14] 3.8e-8 508
15 years 0.02 2.67 [2.04, 3.48] 5.1e-13 435
5 years 0.00 3.22 [2.53, 4.12] 5.4e-21 151
1 year 0.00 2.02 [1.23, 3.33] 5.8e-3 18

Correlations

Index endpoint: GOUT_STRICT – Gout, strict definition
GWS hits: 6

Survival analyses between endpoints

Plot

before Gout, strict definition
after Gout, strict definition

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Drugs most likely to be purchased after Gout, strict definition