Finngen Rheumatological endpoints

rheumatic disease: Inflammatory and degenerative diseases of connective tissue structures, such as arthritis.

Endpoint definition

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Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 56602 33122 23480
Unadjusted prevalence (%) 21.77 22.54 20.76
Mean age at first event (years) 55.42 54.46 56.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [1.36, 1.66] 1.6e-15 5783
15 years 0.01 1.71 [1.56, 1.87] 3.5e-32 4584
5 years 0.00 2.59 [2.37, 2.83] 8.8e-99 1739
1 year 0.00 3.41 [2.94, 3.96] 2.0e-58 440

Correlations

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Index endpoint: RHEUMA_ENDPOINTS – Finngen Rheumatological endpoints
GWS hits: 13

Survival analyses between endpoints

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Plot

before Finngen Rheumatological endpoints
after Finngen Rheumatological endpoints

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Finngen Rheumatological endpoints

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