Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
SLE_FG
Extra metadata
First used in FinnGen datafreeze
DF2
SLE_FG
Similar endpoints
↥List of similar endpoints to
SLE (Finngen)
based on the number of shared cases.
Broader endpoints:
- Systemic lupus erythematosus
- Systemic connective tissue disorders
- Immune disease comorbidities
- Immune disease comorbidities
- Autoimmune diseases related-to ILD
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 687 | 575 | 112 |
| Unadjusted prevalence (%) | 0.26 | 0.39 | 0.10 |
| Mean age at first event (years) | 45.66 | 44.93 | 49.38 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.05 | 3.71 [1.66, 8.25] | 1.3e-3 | 63 |
| 15 years | 0.04 | 5.05 [2.57, 9.90] | 2.5e-6 | 51 |
| 5 years | 0.01 | 8.42 [4.40, 16.08] | 1.1e-10 | 23 |
| 1 year | - | - | - | - |
Correlations
↥
Index endpoint: SLE_FG – SLE (Finngen)
GWS hits: 4
Survival analyses between endpoints
↥Plot
before SLE (Finngen)
after SLE (Finngen)
Loading survival analyses plot
Table
Loading survival analyses table