Systemic lupus erythematosus, unspecified

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M32.9
Cause of death: ICD-10 M32.9

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector SLE_NOS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M32
Name in latin Lupus erythematosus disseminatus non specificatus

Summary Statistics

Key figures

All Female Male
Number of individuals 561 478 83
Unadjusted prevalence (%) 0.22 0.33 0.07
Mean age at first event (years) 47.51 46.87 51.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.26 [2.32, 7.83] 3.0e-6 43
15 years 0.04 5.35 [3.12, 9.18] 1.1e-9 39
5 years 0.01 8.21 [3.94, 17.14] 2.0e-8 19
1 year - - - -

Correlations

Index endpoint: SLE_NOS – Systemic lupus erythematosus, unspecified
GWS hits: 4

Survival analyses between endpoints

Plot

before Systemic lupus erythematosus, unspecified
after Systemic lupus erythematosus, unspecified

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Drugs most likely to be purchased after Systemic lupus erythematosus, unspecified