Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
SLE_STRICT
Extra metadata
First used in FinnGen datafreeze
DF5
SLE_STRICT
Similar endpoints
↥List of similar endpoints to
SLE, strict definition
based on the number of shared cases.
Broader endpoints:
- SLE, ICD10
- Any event in hilmo or specialist outpatient
- Any ICDMAIN event in hilmo or causes of death
- Any prescribed medicine buy
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 660 | 552 | 108 |
| Unadjusted prevalence (%) | 0.25 | 0.38 | 0.10 |
| Mean age at first event (years) | 47.23 | 46.41 | 51.38 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.05 | 3.47 [1.14, 10.53] | 2.8e-2 | 57 |
| 15 years | 0.03 | 5.15 [2.06, 12.88] | 4.6e-4 | 49 |
| 5 years | 0.01 | 9.39 [4.43, 19.90] | 5.0e-9 | 22 |
| 1 year | - | - | - | - |
Correlations
↥
Index endpoint: SLE_STRICT – SLE, strict definition
GWS hits: 6
Survival analyses between endpoints
↥Plot
before SLE, strict definition
after SLE, strict definition
Loading survival analyses plot
Table
Loading survival analyses table