Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
KNEE_ARTHROSIS
Extra metadata
First used in FinnGen datafreeze
DF2
KNEE_ARTHROSIS
Similar endpoints
↥List of similar endpoints to
Gonarthrosis [arthrosis of knee](FG)
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 27798 | 16498 | 11300 |
| Unadjusted prevalence (%) | 10.69 | 11.23 | 9.99 |
| Mean age at first event (years) | 58.71 | 58.90 | 58.43 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.32 [1.15, 1.50] | 4.3e-5 | 2558 |
| 15 years | 0.01 | 1.46 [1.30, 1.63] | 3.0e-11 | 1987 |
| 5 years | 0.00 | 1.91 [1.70, 2.14] | 2.7e-28 | 654 |
| 1 year | 0.00 | 1.71 [1.37, 2.14] | 2.8e-6 | 108 |
Correlations
↥
Index endpoint: KNEE_ARTHROSIS – Gonarthrosis [arthrosis of knee](FG)
GWS hits: 19
Survival analyses between endpoints
↥Plot
before Gonarthrosis [arthrosis of knee](FG)
after Gonarthrosis [arthrosis of knee](FG)
Loading survival analyses plot
Table
Loading survival analyses table