spondyloarthropathy: A group of inflammatory rheumatic diseases associated with arthritis and enthesitis, and often involving the axial skeleton. The most common form of spondyloarthritis is ankylosing spondylitis. Other forms include axial spondyloarthritis, peripheral spondyloarthritis, reactive arthritis, psoriatic arthritis/spondylitis and enteropathic arthritis/spondylitis.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M17
Hospital discharge: ICD-9 7151F|7152F
Hospital discharge: ICD-8 71301
Cause of death: ICD-10 M17
Cause of death: ICD-9 7151F|7152F
Cause of death: ICD-8 71301

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_ARTHROSIS_KNEE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M15-M19
Name in latin Gonarthrosis

Summary Statistics

Key figures

All Female Male
Number of individuals 27798 16498 11300
Unadjusted prevalence (%) 10.69 11.23 9.99
Mean age at first event (years) 58.71 58.90 58.43


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.42 [1.25, 1.60] 4.3e-8 2558
15 years 0.01 1.55 [1.38, 1.74] 5.6e-14 1987
5 years 0.00 1.96 [1.74, 2.20] 1.3e-29 654
1 year 0.00 1.74 [1.39, 2.18] 1.3e-6 108


Index endpoint: M13_ARTHROSIS_KNEE – Gonarthrosis
GWS hits: 20

Survival analyses between endpoints


before Gonarthrosis
after Gonarthrosis

loading spinner Loading survival analyses plot