Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
SYSTSCLE_FG
Extra metadata
First used in FinnGen datafreeze
DF2
SYSTSCLE_FG
Similar endpoints
↥List of similar endpoints to
Systemic sclerosis (FG)
based on the number of shared cases.
Broader endpoints:
- Systemic sclerosis
- Systemic connective tissue disorders
- Immune disease comorbidities
- Immune disease comorbidities
- Autoimmune diseases
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 392 | 320 | 72 |
| Unadjusted prevalence (%) | 0.15 | 0.22 | 0.06 |
| Mean age at first event (years) | 53.53 | 53.54 | 53.53 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.11 | 7.64 [3.99, 14.64] | 8.8e-10 | 33 |
| 15 years | 0.06 | 9.44 [4.90, 18.17] | 1.8e-11 | 30 |
| 5 years | 0.02 | 18.53 [10.04, 34.20] | 1.0e-20 | 20 |
| 1 year | - | - | - | - |
Correlations
↥
Index endpoint: SYSTSCLE_FG – Systemic sclerosis (FG)
GWS hits:
Survival analyses between endpoints
↥Plot
before Systemic sclerosis (FG)
after Systemic sclerosis (FG)
Loading survival analyses plot
Table
Loading survival analyses table