Mixed conductive and sensorineural hearing loss

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H90.6, H90.7, H90.8
Hospital discharge: ICD-9 3892
Cause of death: ICD-10 H90.6, H90.7, H90.8
Cause of death: ICD-9 3892

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector H8_HL_MIX_NAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2262 1214 1048
Unadjusted prevalence (%) 0.87 0.83 0.93
Mean age at first event (years) 59.73 58.11 61.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.35 [0.71, 2.55] 3.6e-1 252
15 years 0.01 1.64 [0.99, 2.72] 5.7e-2 222
5 years 0.00 2.22 [1.49, 3.30] 8.2e-5 77
1 year 0.00 2.42 [1.33, 4.39] 3.8e-3 15

Correlations

Index endpoint: H8_HL_MIX_NAS – Mixed conductive and sensorineural hearing loss
GWS hits: 0

Survival analyses between endpoints

Plot

before Mixed conductive and sensorineural hearing loss
after Mixed conductive and sensorineural hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Mixed conductive and sensorineural hearing loss