Conductive and sensorineural hearing loss

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector H8_CONSENHEARINGLOSS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 20973 10279 10694
Unadjusted prevalence (%) 8.07 6.99 9.46
Mean age at first event (years) 62.35 60.67 63.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.79 [1.55, 2.06] 6.2e-16 2445
15 years 0.01 2.04 [1.81, 2.31] 3.8e-30 2236
5 years 0.00 2.80 [2.50, 3.14] 4.7e-72 1015
1 year 0.00 2.73 [2.26, 3.30] 1.5e-25 192

Correlations

Index endpoint: H8_CONSENHEARINGLOSS – Conductive and sensorineural hearing loss
GWS hits: 11

Survival analyses between endpoints

Plot

before Conductive and sensorineural hearing loss
after Conductive and sensorineural hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Conductive and sensorineural hearing loss