Atrial fibrillation and flutter

atrial fibrillation: A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC)

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 I48
Hospital discharge: ICD-9 4273
Hospital discharge: ICD-8 42792
Cause of death: ICD-10 I48
Cause of death: ICD-9 4273
Cause of death: ICD-8 42792
KELA reimbursements: KELA codes 207|351
KELA reimbursements: ICD-10 I48

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_AF

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I30-I52
Name in latin Fibrillatio atriorum

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 28658 11208 17450
Unadjusted prevalence (%) 11.02 7.63 15.43
Mean age at first event (years) 67.08 69.51 65.53


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.57 [3.20, 3.99] <1e-100 6326
15 years - - - -
5 years - - - -
1 year - - - -


Index endpoint: I9_AF – Atrial fibrillation and flutter
GWS hits: 54

Survival analyses between endpoints


before Atrial fibrillation and flutter
after Atrial fibrillation and flutter

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Drugs most likely to be purchased after Atrial fibrillation and flutter