Atrial fibrillation and flutter with reimbursement

atrial fibrillation: A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC)

Endpoint definition

FinnGen phenotype data
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Filter registries KELA purch., KELA reimb.

KELA reimbursements: KELA codes 207|351

Check pre-conditions None

Include endpoints None

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Check conditions

I9_AF

Apply sex-specific rule None

diagram downward connector I9_AF_REIMB

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 15253 6527 8726
Unadjusted prevalence (%) 5.87 4.44 7.72
Mean age at first event (years) 70.15 71.92 68.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.67 [1.28, 2.17] 1.7e-4 1194
15 years 0.01 1.94 [1.59, 2.36] 4.0e-11 989
5 years 0.00 3.17 [2.73, 3.68] 5.5e-51 562
1 year 0.00 5.42 [4.47, 6.56] 4.6e-67 241

Correlations

Index endpoint: I9_AF_REIMB – Atrial fibrillation and flutter with reimbursement
GWS hits: 39

Survival analyses between endpoints

Plot

before Atrial fibrillation and flutter with reimbursement
after Atrial fibrillation and flutter with reimbursement

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Atrial fibrillation and flutter with reimbursement