Cardiomyopathies, Primary/intrinsic

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I42.0, I42.1, I42.3, I42.4, I42.5
Hospital discharge: ICD-9 4250A|4254A
Cause of death: ICD-10 I42.0, I42.1, I42.3, I42.4, I42.5
Cause of death: ICD-9 4250A|4254A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_CARDMPRI

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2685 741 1944
Unadjusted prevalence (%) 1.03 0.50 1.72
Mean age at first event (years) 59.15 57.48 59.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 6.13 [3.74, 10.05] 5.8e-13 602
15 years 0.05 7.49 [5.28, 10.64] 1.8e-29 566
5 years - - - -
1 year - - - -

Correlations

Index endpoint: I9_CARDMPRI – Cardiomyopathies, Primary/intrinsic
GWS hits: 5

Survival analyses between endpoints

Plot

before Cardiomyopathies, Primary/intrinsic
after Cardiomyopathies, Primary/intrinsic

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathies, Primary/intrinsic