Diseases of the circulatory system

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I00-I99
Hospital discharge: ICD-9 39|4[0-5]
Hospital discharge: ICD-8 39|4[0-5]
Cause of death: ICD-10 I00-I99
Cause of death: ICD-9 39|4[0-5]
Cause of death: ICD-8 39|4[0-5]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector IX_CIRCULATORY

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 123508 63598 59910
Unadjusted prevalence (%) 47.50 43.28 52.98
Mean age at first event (years) 52.99 50.92 55.19

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 6.02 [5.64, 6.43] <1e-100 18772
15 years 0.03 7.76 [7.23, 8.32] <1e-100 15003
5 years 0.01 12.90 [11.64, 14.30] <1e-100 6459
1 year 0.01 33.65 [27.20, 41.63] <1e-100 2937

Correlations

Index endpoint: IX_CIRCULATORY – Diseases of the circulatory system
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the circulatory system
after Diseases of the circulatory system

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of the circulatory system