Heart failure,strict

systolic heart failure: Heart failure caused by abnormal myocardial contraction during systole leading to defective cardiac emptying.

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 I11.0, I13.0, I13.2, I50
Hospital discharge: ICD-9 4029B|428
Hospital discharge: ICD-8 42700|42710|428|7824
Cause of death: ICD-10 I11.0, I13.0, I13.2, I50
Cause of death: ICD-9 4029B|428
Cause of death: ICD-8 42700|42710|428|7824
KELA reimbursements: KELA codes 201
Medicine purchases: ATC C03CA01|C03EB01
Medicine purchases: ATC: other data required require also another data source

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HEARTFAIL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6

Summary Statistics

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Key figures

All Female Male
Number of individuals 15829 6233 9596
Unadjusted prevalence (%) 6.09 4.24 8.49
Mean age at first event (years) 66.63 67.45 66.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: I9_HEARTFAIL – Heart failure,strict
GWS hits: 2

Survival analyses between endpoints

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Plot

before Heart failure,strict
after Heart failure,strict

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Heart failure,strict

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