Heart failure, not strict

systolic heart failure: Heart failure caused by abnormal myocardial contraction during systole leading to defective cardiac emptying.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 I11.0, I13.0, I13.2, I50
Hospital discharge: ICD-9 4029B|428
Hospital discharge: ICD-8 42700|42710|428|7824
Cause of death: ICD-10 I11.0, I13.0, I13.2, I50
Cause of death: ICD-9 4029B|428
Cause of death: ICD-8 42700|42710|428|7824
KELA reimbursements: KELA codes 201
Medicine purchases: ATC C03CA01|C03EB01
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HEARTFAIL_NS

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 30447 14130 16317
Unadjusted prevalence (%) 11.71 9.62 14.43
Mean age at first event (years) 65.81 65.09 66.43


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 6.53 [5.92, 7.19] <1e-100 9591
15 years 0.06 7.24 [6.66, 7.87] <1e-100 8876
5 years 0.01 9.85 [9.06, 10.71] <1e-100 4818
1 year 0.00 13.84 [12.04, 15.91] <1e-100 1485


Index endpoint: I9_HEARTFAIL_NS – Heart failure, not strict
GWS hits: 3

Survival analyses between endpoints


before Heart failure, not strict
after Heart failure, not strict

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Heart failure, not strict