Hypertrophic cardiomyopathy

hypertrophic cardiomyopathy: A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I42.1, I42.2
Cause of death: ICD-10 I42.1, I42.2

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HYPERTROCARDMYOP

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 659 266 393
Unadjusted prevalence (%) 0.25 0.18 0.35
Mean age at first event (years) 57.15 55.21 58.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 6.50 [3.74, 11.29] 3.0e-11 127
15 years 0.05 7.82 [4.90, 12.48] 6.7e-18 119
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: I9_HYPERTROCARDMYOP – Hypertrophic cardiomyopathy
GWS hits: 18

Survival analyses between endpoints

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Plot

before Hypertrophic cardiomyopathy
after Hypertrophic cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertrophic cardiomyopathy

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