Hypertrophic cardiomyopathy

hypertrophic cardiomyopathy: A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I42.1, I42.2
Cause of death: ICD-10 I42.1, I42.2

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HYPERTROCARDMYOP

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 659 266 393
Unadjusted prevalence (%) 0.25 0.18 0.35
Mean age at first event (years) 57.15 55.21 58.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 6.50 [3.74, 11.29] 3.0e-11 127
15 years 0.05 7.82 [4.90, 12.48] 6.7e-18 119
5 years - - - -
1 year - - - -

Correlations

Index endpoint: I9_HYPERTROCARDMYOP – Hypertrophic cardiomyopathy
GWS hits: 18

Survival analyses between endpoints

Plot

before Hypertrophic cardiomyopathy
after Hypertrophic cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertrophic cardiomyopathy