Nonischemic cardiomyopathy

dilated cardiomyopathy: Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I42.0, I51.1
Hospital discharge: ICD-9 4281
Cause of death: ICD-10 I42.0, I51.1
Cause of death: ICD-9 4281

Check pre-conditions None

Include endpoints None

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Check conditions

not I9_IHD
and not I9_HYPERTROCARDMYOP

Apply sex-specific rule None

diagram downward connector I9_NONISCHCARDMYOP_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 1105 313 792
Unadjusted prevalence (%) 0.42 0.21 0.70
Mean age at first event (years) 56.88 55.39 57.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.13 [1.09, 9.02] 3.4e-2 152
15 years 0.03 4.55 [2.06, 10.05] 1.8e-4 145
5 years 0.01 8.56 [4.98, 14.72] 8.0e-15 75
1 year - - - -

Correlations

Index endpoint: I9_NONISCHCARDMYOP_STRICT – Nonischemic cardiomyopathy
GWS hits: 1

Survival analyses between endpoints

Plot

before Nonischemic cardiomyopathy
after Nonischemic cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nonischemic cardiomyopathy