Stroke, including SAH

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I60, I61, I63, I64
Hospital discharge: ICD-9 430|431|4330A|4331A|4339A|4340A|4341A|4349A|436
Hospital discharge: ICD-8 430|431|433|434|436
Hospital discharge: excluded ICD-10 I63.6
Hospital discharge: excluded ICD-8 43101|43191
Cause of death: ICD-10 I60, I61, I63, I64
Cause of death: ICD-9 430|431|4330A|4331A|4339A|4340A|4341A|4349A|436
Cause of death: ICD-8 430|431|433|434|436
Cause of death: excluded ICD-10 I63.6
Cause of death: excluded ICD-8 43101|43191

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_STR_SAH

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 15435 6434 9001
Unadjusted prevalence (%) 5.94 4.38 7.96
Mean age at first event (years) 64.62 64.52 64.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.88 [4.28, 5.57] <1e-100 5178
15 years 0.04 5.77 [5.17, 6.44] <1e-100 4772
5 years - - - -
1 year - - - -

Correlations

Index endpoint: I9_STR_SAH – Stroke, including SAH
GWS hits: 1

Survival analyses between endpoints

Plot

before Stroke, including SAH
after Stroke, including SAH

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Stroke, including SAH