Thromboangiitis obliterans

thromboangiitis obliterans: Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I73.1
Hospital discharge: ICD-9 4431A
Hospital discharge: ICD-8 44310
Cause of death: ICD-10 I73.1
Cause of death: ICD-9 4431A
Cause of death: ICD-8 44310

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_THROMBANG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I73
Name in latin Tromboangi(i)tis obliterans (Bürger)

Summary Statistics

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Key figures

All Female Male
Number of individuals 70 27 43
Unadjusted prevalence (%) 0.03 0.02 0.04
Mean age at first event (years) 48.68 46.24 50.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: I9_THROMBANG – Thromboangiitis obliterans
GWS hits:

Survival analyses between endpoints

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Plot

before Thromboangiitis obliterans
after Thromboangiitis obliterans

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Thromboangiitis obliterans

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