Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

laryngeal disease: A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma. [database_cross_reference: NCIT:P378]

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 J34, J38, J39
Hospital discharge: ICD-9 478
Hospital discharge: ICD-8 508
Hospital discharge: excluded ICD-8 50803
Cause of death: ICD-10 J34, J38, J39
Cause of death: ICD-9 478
Cause of death: ICD-8 508
Cause of death: excluded ICD-8 50803

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector J10_VOCALLARYNX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 12147 6023 6124
Unadjusted prevalence (%) 4.67 4.10 5.42
Mean age at first event (years) 47.62 46.27 48.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.86 [1.42, 2.44] 7.0e-6 755
15 years 0.02 2.33 [1.85, 2.93] 4.2e-13 595
5 years 0.00 4.29 [3.49, 5.27] 4.5e-44 265
1 year 0.00 7.39 [5.60, 9.75] 1.8e-45 85

Correlations

Index endpoint: J10_VOCALLARYNX – Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
GWS hits: 1

Survival analyses between endpoints

Plot

before Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
after Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

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Drugs most likely to be purchased after Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified