Vocal cord dysfunction

human african trypanosomiasis: A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 J38.3
Cause of death: ICD-10 J38.3

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector VOCALCORDDYS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J38
Name in latin Alii morbi plicarum vocalium

Summary Statistics

Key figures

All Female Male
Number of individuals 624 291 333
Unadjusted prevalence (%) 0.24 0.20 0.29
Mean age at first event (years) 54.93 52.05 57.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.38 [1.74, 11.06] 1.8e-3 53
15 years 0.03 4.66 [1.91, 11.39] 7.4e-4 48
5 years 0.01 9.18 [4.72, 17.84] 6.4e-11 25
1 year - - - -

Correlations

Index endpoint: VOCALCORDDYS – Vocal cord dysfunction
GWS hits: 0

Survival analyses between endpoints

Plot

before Vocal cord dysfunction
after Vocal cord dysfunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vocal cord dysfunction