Other diseases of oesophagus

DOID EFO MESH SNOMED PheWeb

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9

Hospital discharge: ICD-9 530[5-9]

Hospital discharge: ICD-8 5302|5309

Hospital discharge: excluded ICD-10 K22.7

Cause of death: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9

Cause of death: ICD-9 530[5-9]

Cause of death: ICD-8 5302|5309

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

K11_OTHDISOES

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diseases of oesophagus based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1844	812	1032
Unadjusted prevalence (%)	0.71	0.55	0.91
Mean age at first event (years)	53.43	52.06	54.52

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.42 [0.96, 2.10]	7.9e-2	343
15 years	0.01	1.62 [1.16, 2.25]	4.4e-3	258
5 years	0.00	2.73 [1.99, 3.75]	4.6e-10	113
1 year	0.00	4.03 [2.58, 6.28]	8.4e-10	30

Correlations

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Index endpoint: K11_OTHDISOES – Other diseases of oesophagus
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other diseases of oesophagus
after Other diseases of oesophagus

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Table

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Drugs most likely to be purchased after Other diseases of oesophagus

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