Diseases of oesophagus, stomach and duodenum

gastric mucosal hypertrophy: MC)nC)trier disease (MD) is a rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K20, K20#, K20-K31
Cause of death: ICD-10 K20, K20#, K20-K31

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 35387 19417 15970
Unadjusted prevalence (%) 13.61 13.21 14.12
Mean age at first event (years) 54.56 53.43 55.94

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.55 [2.28, 2.85] 8.1e-62 4672
15 years 0.02 3.02 [2.76, 3.31] <1e-100 3963
5 years 0.01 5.27 [4.81, 5.77] <1e-100 1973
1 year 0.00 9.70 [8.43, 11.15] <1e-100 705

Correlations

Index endpoint: K11_OESSTODUO – Diseases of oesophagus, stomach and duodenum
GWS hits: 0

Survival analyses between endpoints

Plot

before Diseases of oesophagus, stomach and duodenum
after Diseases of oesophagus, stomach and duodenum

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Drugs most likely to be purchased after Diseases of oesophagus, stomach and duodenum