Ulcerative colitis (strict definition, require KELA)

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K51
Hospital discharge: ICD-9 556
Hospital discharge: ICD-8 5631|569
Hospital discharge: excluded ICD-9 5564A
Cause of death: ICD-10 K51
Cause of death: ICD-9 556
Cause of death: ICD-8 5631|569
Cause of death: excluded ICD-9 5564A

Check pre-conditions None

Include endpoints None

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Check conditions

K11_KELAUC

Apply sex-specific rule None

diagram downward connector K11_UC_STRICT

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Colitis ulcerosa

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 3276 1709 1567
Unadjusted prevalence (%) 1.26 1.16 1.39
Mean age at first event (years) 40.24 38.20 42.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.91 [0.58, 1.44] 6.9e-1 105
15 years 0.01 0.81 [0.52, 1.27] 3.6e-1 62
5 years 0.00 0.86 [0.44, 1.68] 6.6e-1 14
1 year - - - -

Correlations

Index endpoint: K11_UC_STRICT – Ulcerative colitis (strict definition, require KELA)
GWS hits: 13

Survival analyses between endpoints

Plot

before Ulcerative colitis (strict definition, require KELA)
after Ulcerative colitis (strict definition, require KELA)

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Drugs most likely to be purchased after Ulcerative colitis (strict definition, require KELA)