Ulcerative colitis

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K51
Hospital discharge: ICD-9 556
Hospital discharge: ICD-8 5631|569
Hospital discharge: excluded ICD-9 5564A
Cause of death: ICD-10 K51
Cause of death: ICD-9 556
Cause of death: ICD-8 5631|569
Cause of death: excluded ICD-9 5564A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_ULCER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50-K52
Name in latin Colitis ulcerosa

Similar endpoints

List of similar endpoints to Ulcerative colitis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5348 2836 2512
Unadjusted prevalence (%) 2.06 1.93 2.22
Mean age at first event (years) 42.19 40.61 43.96


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.90 [1.45, 2.49] 2.8e-6 372
15 years 0.01 2.06 [1.63, 2.61] 1.6e-9 275
5 years 0.00 3.33 [2.57, 4.30] 4.7e-20 107
1 year 0.00 5.55 [3.73, 8.27] 2.9e-17 32


Index endpoint: K11_ULCER – Ulcerative colitis
GWS hits: 12

Survival analyses between endpoints


before Ulcerative colitis
after Ulcerative colitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative colitis