Noninfective enteritis and colitis

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K50-K52
Cause of death: ICD-10 K50-K52

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 10697 6026 4671
Unadjusted prevalence (%) 4.11 4.10 4.13
Mean age at first event (years) 44.07 43.02 45.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.73 [2.29, 3.24] 3.7e-30 1013
15 years 0.02 3.04 [2.59, 3.56] 6.2e-43 829
5 years 0.01 5.28 [4.47, 6.24] 9.5e-86 434
1 year 0.00 9.69 [7.73, 12.15] 3.6e-86 165

Correlations

Index endpoint: K11_ENERCOLNONINF – Noninfective enteritis and colitis
GWS hits: 11

Survival analyses between endpoints

Plot

before Noninfective enteritis and colitis
after Noninfective enteritis and colitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Noninfective enteritis and colitis