Ulcerative colitis, NAS

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K51.9
Cause of death: ICD-10 K51.9

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector ULCERNAS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Colitis ulcerosa non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 2729 1515 1214
Unadjusted prevalence (%) 1.05 1.03 1.07
Mean age at first event (years) 45.86 44.45 47.63

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.95 [1.89, 4.60] 2.1e-6 179
15 years 0.02 3.49 [2.41, 5.05] 3.6e-11 158
5 years 0.01 6.28 [4.48, 8.81] 1.6e-26 76
1 year 0.00 11.06 [6.91, 17.71] 1.5e-23 25

Correlations

Index endpoint: ULCERNAS – Ulcerative colitis, NAS
GWS hits: 5

Survival analyses between endpoints

Plot

before Ulcerative colitis, NAS
after Ulcerative colitis, NAS

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Drugs most likely to be purchased after Ulcerative colitis, NAS