Speech and linguistic disorders

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F80, F81
Hospital discharge: ICD-9 315[0-3]|3159
Hospital discharge: ICD-8 31610
Cause of death: ICD-10 F80, F81
Cause of death: ICD-9 315[0-3]|3159
Cause of death: ICD-8 31610

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector KRA_PSY_SPEELING

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1554 735 819
Unadjusted prevalence (%) 0.60 0.50 0.72
Mean age at first event (years) 17.66 20.21 15.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.17 12.42 [5.66, 27.28] 3.4e-10 36
15 years 0.09 12.99 [6.34, 26.62] 2.5e-12 31
5 years 0.02 17.09 [8.08, 36.13] 1.1e-13 25
1 year - - - -

Correlations

Index endpoint: KRA_PSY_SPEELING – Speech and linguistic disorders
GWS hits: 0

Survival analyses between endpoints

Plot

before Speech and linguistic disorders
after Speech and linguistic disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Speech and linguistic disorders