Speech and linguistic disorders

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F80, F81
Hospital discharge: ICD-9 315[0-3]|3159
Hospital discharge: ICD-8 31610
Cause of death: ICD-10 F80, F81
Cause of death: ICD-9 315[0-3]|3159
Cause of death: ICD-8 31610

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector KRA_PSY_SPEELING

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1554 735 819
Unadjusted prevalence (%) 0.60 0.50 0.72
Mean age at first event (years) 17.66 20.21 15.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.17 12.42 [5.66, 27.28] 3.4e-10 36
15 years 0.09 12.99 [6.34, 26.62] 2.5e-12 31
5 years 0.02 17.09 [8.08, 36.13] 1.1e-13 25
1 year - - - -

Correlations

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Index endpoint: KRA_PSY_SPEELING – Speech and linguistic disorders
GWS hits: 0

Survival analyses between endpoints

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Plot

before Speech and linguistic disorders
after Speech and linguistic disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Speech and linguistic disorders

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