Bullous disorders

vesiculobullous skin disease: Skin diseases characterized by local or general distributions of vesicles and bullae (i.e. blisters). Both vesicles and bullae are fluid-filled lesions, distinguished by size (vesicles being less than 5–10 mm and bullae being larger than 5–10 mm). Vesiculobullous diseases are classified according to the site and mode of blister formation. Lesions can appear spontaneously or be precipitated by infection, trauma, or sunlight. Etiologies include immunologic and genetic factors. In the case of vesiculobullous diseases which are also immune disorders, the term immunobullous is sometimes used. (From Scientific American Medicine, 1990, and Wikipedia)

Summary Statistics

Key figures

All Female Male
Number of individuals 907 502 405
Unadjusted prevalence (%) 0.35 0.34 0.36
Mean age at first event (years) 55.15 52.94 57.89


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.61 [1.31, 5.19] 6.3e-3 135
15 years 0.02 3.24 [1.80, 5.81] 8.2e-5 121
5 years - - - -
1 year - - - -


Index endpoint: L12_BULLOUS – Bullous disorders
GWS hits: 2

Survival analyses between endpoints


before Bullous disorders
after Bullous disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Bullous disorders