Dermatitis herpetiformis

dermatitis herpetiformis: Dermatitis herpetiformis (DH) is a chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. DH may also appear as a consequence of gluten intolerance.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L13.0
Hospital discharge: ICD-9 6940A|6942
Hospital discharge: ICD-8 693
Cause of death: ICD-10 L13.0
Cause of death: ICD-9 6940A|6942
Cause of death: ICD-8 693

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_DERMATHERP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L13
Name in latin Dermatitis herpetiformis

Summary Statistics

Key figures

All Female Male
Number of individuals 338 196 142
Unadjusted prevalence (%) 0.13 0.13 0.13
Mean age at first event (years) 44.90 42.67 47.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: L12_DERMATHERP – Dermatitis herpetiformis
GWS hits: 8

Survival analyses between endpoints

Plot

before Dermatitis herpetiformis
after Dermatitis herpetiformis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Dermatitis herpetiformis